Hormone Replacement Therapy

WHAT IS COMPOUNDED BHRT?Feel yourself again with BHRT

Compounded BHRT, or Bio-Identical Hormone Replacement Therapy, is a specialized approach to hormone replacement therapy that involves the custom formulation of hormones to match an individual's unique hormone profile. It is primarily used to address hormonal imbalances, particularly in menopausal or postmenopausal women, but can also be applied to men and individuals with other hormonal issues.

The term "bio-identical" is key to understanding this therapy. Bio-identical hormones are derived from natural sources such as soy or yam plants and are designed to be structurally identical to the hormones produced by the human body. This contrasts with synthetic hormones, which have a different chemical structure and are not naturally produced within our bodies.

The process of compounded BHRT typically involves the following steps:

Hormone Assessment: A healthcare provider evaluates the patient's symptoms, medical history, and hormone levels through blood tests or other diagnostic methods to determine the specific hormonal imbalances.

Custom Formulation: Based on the assessment, a compounding pharmacist works with the healthcare provider to create a customized hormone treatment plan. The pharmacist formulates the medication, which may include hormones like estradiol, progesterone, testosterone, or other hormones in specific dosages to address the patient's unique needs.

Prescription and Monitoring: The healthcare provider prescribes the compounded BHRT medication, and the patient is closely monitored to ensure the treatment is effective and that hormone levels are balanced appropriately.

The goal of compounded BHRT is to provide a more personalized and tailored approach to hormone therapy. Advocates of compounded BHRT claim that it may offer benefits such as reduced side effects and a more natural hormone replacement experience compared to conventional hormone replacement therapy using commercially available synthetic hormones. However, it's important to note that the safety and efficacy of compounded BHRT are subjects of ongoing debate and research.

Patients considering compounded BHRT should work closely with a knowledgeable healthcare provider who can carefully assess their individual needs, monitor their progress, and ensure that the therapy is safe and effective for their specific situation. Additionally, individuals should be aware that regulations and standards for compounding pharmacies can vary by location, so it's important to choose a reputable compounding pharmacy and healthcare provider for this type of treatment.


Bio-Identical Hormone Replacement Therapy (BHRT) is available in a variety of dosage forms to suit individual preferences and medical needs. The choice of dosage form can depend on factors such as the patient's specific hormonal imbalances, their symptoms, and their healthcare provider's recommendations. Here are some common dosage forms for BHRT:

  • Creams:

Topical creams are a popular dosage form for BHRT. Patients apply the cream to their skin, typically on areas with thinner skin, such as the inner forearm, wrists, or the inner thigh. These creams are absorbed through the skin and can deliver hormones like estradiol, progesterone, or testosterone.

  • Gels:

Hormone gels are applied topically to the skin in a similar manner to creams. They are absorbed through the skin and provide a controlled release of hormones.

  • Oral Capsules or Tablets:

Some BHRT medications are available in oral form. These can be taken by mouth and may contain various hormones in specific dosages. This form may be suitable for those who prefer the convenience of oral medications.

  • Sublingual Tablets:

Sublingual BHRT tablets are placed under the tongue and absorbed directly into the bloodstream. This can lead to more rapid hormone absorption and may be preferred by some individuals.

  • Vaginal Forms:

Some BHRT treatments are formulated as vaginal creams, suppositories, or tablets. These are designed for women dealing with issues related to vaginal dryness, atrophy, or urinary symptoms associated with hormonal changes.

The choice of dosage form should be made by a healthcare provider in conjunction with our expert compounding pharmacist who can assess the patient's specific needs and recommend the most appropriate form based on their hormone levels, symptoms, and individual preferences. It's essential to follow your healthcare provider's guidance and instructions carefully when using BHRT to ensure safe and effective hormone replacement.


Bio-Identical Hormone Replacement Therapy (BHRT) is typically recommended for individuals who have specific hormonal imbalances or experience symptoms related to hormonal changes. The decision to use BHRT is typically made in consultation with a healthcare provider who can assess a patient's individual needs, considering their medical history, symptoms, and hormone levels. Here are some common groups of people who may benefit from BHRT:

Menopausal and Perimenopausal Women: BHRT is often prescribed to women who are going through menopause or perimenopause. These individuals may experience symptoms like hot flashes, night sweats, mood swings, vaginal dryness, and a loss of bone density due to a decline in estrogen and other hormone levels.

Postmenopausal Women: BHRT may be recommended to postmenopausal women who are at risk of osteoporosis and want to maintain bone health. Hormone therapy can also help alleviate postmenopausal symptoms.

Individuals with Hormone Imbalances: Men and women with specific hormonal imbalances, such as low testosterone in men or irregularities in thyroid hormones, may be candidates for BHRT to address their hormonal deficiencies.

Individuals with Symptoms of Hormone Deficiency: BHRT can be considered for those experiencing symptoms related to hormonal imbalances, such as fatigue, low libido, mood changes, weight gain, and sleep disturbances.

Women with Severe PMS or PMDD: Some women with severe premenstrual symptoms or premenstrual dysphoric disorder (PMDD) may benefit from BHRT to help regulate hormone fluctuations and alleviate symptoms.

Hormone-Related Conditions: BHRT can be used in some cases to manage hormone-related conditions, such as polycystic ovary syndrome (PCOS) or endometriosis.

Individuals with Surgical Menopause: Women who undergo surgical menopause due to the removal of the ovaries may consider BHRT to address the sudden hormonal changes.

It's important to emphasize that the decision to use BHRT should be based on a thorough evaluation by a healthcare provider. BHRT is not suitable for everyone, and potential risks and benefits need to be carefully considered on an individual basis. Additionally, BHRT should be administered under the supervision of a qualified healthcare professional who can monitor hormone levels and adjust treatment as necessary to ensure safety and effectiveness.

Speak to our Pharmacist to see if BHRT is right for you!


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The Prescription Center is an independent, family-owned and operated pharmacy located in Concord, New Hampshire. For over 50 years, we..